With 3 IBiSA platforms (PISSARO, PRIMACEN, SCAC) and 2 establishments that use animals for scientific purposes, the « High-tech Research infrastructures for Life Sciences » (HeRacLeS) research infrastructure offers a continuum ranging from synthesis of a molecule of interest up to the study of its effects in vivo. HeRacLeS thus covers all the activities allowing the synthesis of peptides, the analysis of the expression of genes and proteins, localization by light and electron microscopy, the study of cellular and tissue activities as well as functional and behavioral explorations in animals.

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Dernières publications Carole Lartigue, Bastien Lambert, Fabien Rideau, Yorick Dahan, Marion Decossas, et al.. Cytoskeletal components can turn wall-less spherical bacteria into kinking helices. Nature Communications, 2022, 13 (1), pp.6930. ⟨10.1038/s41467-022-34478-0⟩. ⟨hal-03914264⟩ Jaber Dehghani, Ali Movafeghi, Elodie Mathieu-Rivet, Narimane Mati-Baouche, Sébastien Calbo, et al.. Microalgae as an Efficient Vehicle for the Production and Targeted Delivery of Therapeutic Glycoproteins against SARS-CoV-2 Variants. Marine drugs, 2022, 20 (11), pp.657. ⟨10.3390/md20110657⟩. ⟨hal-03826579⟩ Pauline Tirelle, Colin Salaün, Alexandre Kauffmann, Christine Bôle-Feysot, Charlène Guérin, et al.. Intestinal Epithelial Toll-like Receptor 4 Deficiency Modifies the Response to the Activity-Based Anorexia Model in a Sex-Dependent Manner: A Preliminary Study. Nutrients, 2022, 14 (17), pp.3607. ⟨10.3390/nu14173607⟩. ⟨hal-03791749⟩ Maxime Endress, Céline Zatylny-Gaudin, Jérôme Leprince, Benjamin Lefranc, Erwan Corre, et al.. Structural and functional characterization of orcokinin B-like neuropeptides in the cuttlefish ($Sepia\ officinalis$). Marine drugs, 2022, 20 (8), pp.505. ⟨10.3390/md20080505⟩. ⟨hal-03777035⟩ Guillaume Font, Marie-Laure Walet-Balieu, Marie Petit, Carole Burel, Maud Maho-Vaillant, et al.. IgG N-Glycosylation from Patients with Pemphigus Treated with Rituximab. Biomedicines, 2022, 10 (8), pp.1774. ⟨10.3390/biomedicines10081774⟩. ⟨hal-03738179⟩

Contact Phone: +33 (0) 235.14.7048 Email: ludovic.galas@inserm.fr Address : Dr Ludovic Galas, IR Inserm, HDR UFR des Sciences et Techniques Université de Rouen Normandie Bâtiment CURIB 25 rue Lucien Tesnière 76130 MONT-SAINT-AIGNAN Cedex Access Map